7L0F

Monobody 12VC3 Bound to HRAS(WT)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0007165	biological_process	signal transduction
A	0016020	cellular_component	membrane
E	0003924	molecular_function	GTPase activity
E	0005525	molecular_function	GTP binding
E	0007165	biological_process	signal transduction
E	0016020	cellular_component	membrane
G	0003924	molecular_function	GTPase activity
G	0005525	molecular_function	GTP binding
G	0007165	biological_process	signal transduction
G	0016020	cellular_component	membrane
L	0003924	molecular_function	GTPase activity
L	0005525	molecular_function	GTP binding
L	0007165	biological_process	signal transduction
L	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:16698776

Chain	Residue	Details
E	GLY13
A	SER145
G	GLY13
G	VAL29
G	ALA59
G	ASN116
G	SER145
L	GLY13
L	VAL29
L	ALA59
L	ASN116
E	VAL29
L	SER145
E	ALA59
E	ASN116
E	SER145
A	GLY13
A	VAL29
A	ALA59
A	ASN116

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12

Chain	Residue	Details
E	MET1
A	MET1
G	MET1
L	MET1

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12

Chain	Residue	Details
E	THR2
A	THR2
G	THR2
L	THR2

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:9020151

Chain	Residue	Details
E	CYS118
A	CYS118
G	CYS118
L	CYS118

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486, ECO:0000269|PubMed:8626575, ECO:0000269|PubMed:8626586, ECO:0000269|PubMed:9632667

Chain	Residue	Details
E	THR35
A	THR35
G	THR35
L	THR35

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