7K0A
Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA
Summary for 7K0A
Entry DOI | 10.2210/pdb7k0a/pdb |
Descriptor | Puromycin N-acetyltransferase, N-Acetylpuromycin, COENZYME A, ... (7 entities in total) |
Functional Keywords | enzyme acetyletransferase complex selection marker, antibiotic, transferase |
Biological source | Streptomyces alboniger |
Total number of polymer chains | 2 |
Total formula weight | 48699.96 |
Authors | Peat, T.S.,Caputo, A.T.,Newman, J.,Adams, T.E. (deposition date: 2020-09-03, release date: 2021-03-17, Last modification date: 2023-10-18) |
Primary citation | Caputo, A.T.,Eder, O.M.,Bereznakova, H.,Pothuis, H.,Ardevol, A.,Newman, J.,Nuttall, S.,Peat, T.S.,Adams, T.E. Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins. Sci Rep, 11:5247-5247, 2021 Cited by PubMed: 33664348DOI: 10.1038/s41598-021-84551-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report