7JZ4
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
Summary for 7JZ4
Entry DOI | 10.2210/pdb7jz4/pdb |
Descriptor | MGD21 heavy chain, MGD21 light chain, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | lair1, insertion, antibody, rifin, malaria, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 126126.51 |
Authors | Xu, K.,Kwong, P.D. (deposition date: 2020-09-01, release date: 2021-05-26, Last modification date: 2024-10-09) |
Primary citation | Xu, K.,Wang, Y.,Shen, C.H.,Chen, Y.,Zhang, B.,Liu, K.,Tsybovsky, Y.,Wang, S.,Farney, S.K.,Gorman, J.,Stephens, T.,Verardi, R.,Yang, Y.,Zhou, T.,Chuang, G.Y.,Lanzavecchia, A.,Piccoli, L.,Kwong, P.D. Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12:4226-4226, 2021 Cited by PubMed: 34244481DOI: 10.1038/s41467-021-24291-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.747 Å) |
Structure validation
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