7JO9
1:1 cGAS-nucleosome complex
Summary for 7JO9
Entry DOI | 10.2210/pdb7jo9/pdb |
EMDB information | 22408 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total) |
Functional Keywords | cgas, nucleosome, cyclic gmp-amp synthase, dna binding protein-dna-transferase complex, dna binding protein/dna/transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 243022.66 |
Authors | Boyer, J.A.,Spangler, C.J.,Strauss, J.D.,Cesmat, A.P.,Liu, P.,McGinty, R.K.,Zhang, Q. (deposition date: 2020-08-06, release date: 2020-09-16, Last modification date: 2024-03-06) |
Primary citation | Boyer, J.A.,Spangler, C.J.,Strauss, J.D.,Cesmat, A.P.,Liu, P.,McGinty, R.K.,Zhang, Q. Structural basis of nucleosome-dependent cGAS inhibition. Science, 370:450-454, 2020 Cited by PubMed: 32913000DOI: 10.1126/science.abd0609 PDB entries with the same primary citation |
Experimental method |
Structure validation
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