7FD8
Thermostabilised full length human mGluR5-5M bound with L-quisqualic acid
Summary for 7FD8
Entry DOI | 10.2210/pdb7fd8/pdb |
Related | 7P2L |
EMDB information | 31536 31537 |
Descriptor | Metabotropic glutamate receptor 5, 2-acetamido-2-deoxy-beta-D-glucopyranose, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ... (4 entities in total) |
Functional Keywords | g protein coupled receptors, signal transduction, metabotropic glutamate receptor 5 (grm5), membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 195702.07 |
Authors | Vinothkumar, K.R.,Cannone, G.,Lebon, G. (deposition date: 2021-07-16, release date: 2021-09-08, Last modification date: 2021-10-13) |
Primary citation | Nasrallah, C.,Cannone, G.,Briot, J.,Rottier, K.,Berizzi, A.E.,Huang, C.Y.,Quast, R.B.,Hoh, F.,Baneres, J.L.,Malhaire, F.,Berto, L.,Dumazer, A.,Font-Ingles, J.,Gomez-Santacana, X.,Catena, J.,Kniazeff, J.,Goudet, C.,Llebaria, A.,Pin, J.P.,Vinothkumar, K.R.,Lebon, G. Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36:109648-109648, 2021 Cited by PubMed: 34469715DOI: 10.1016/j.celrep.2021.109648 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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