7EU7
Structure of the human GluN1-GluN2A NMDA receptor in complex with S-ketamine, glycine and glutamate
Summary for 7EU7
Entry DOI | 10.2210/pdb7eu7/pdb |
EMDB information | 31308 |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | nmda receptor, ketamine, enantiomer, rapid antidepressant, cryo-em structure, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 384735.30 |
Authors | |
Primary citation | Zhang, Y.,Ye, F.,Zhang, T.,Lv, S.,Zhou, L.,Du, D.,Lin, H.,Guo, F.,Luo, C.,Zhu, S. Structural basis of ketamine action on human NMDA receptors. Nature, 596:301-305, 2021 Cited by PubMed: 34321660DOI: 10.1038/s41586-021-03769-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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