7EU7
Structure of the human GluN1-GluN2A NMDA receptor in complex with S-ketamine, glycine and glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 847 | 95236.1 | 2 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (Human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2A | polymer | 841 | 94136.0 | 2 | UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (Human) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A,hNR2A |
| 3 | AA, CA, DA, E, EA... (C, D, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) | |||
| 4 | BA, N (C, A) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | |||
| 5 | FA, R (D, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 6 | GA (D) | (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one | non-polymer | 237.7 | 1 | Chemie (JC9) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 378744.2 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 5991.1 | |
| All* | Total formula weight | 384735.3 |
