7EJX
Structure of the GPR88-Gi1 signaling complex bound to a synthetic ligand
Summary for 7EJX
Entry DOI | 10.2210/pdb7ejx/pdb |
EMDB information | 31164 |
Descriptor | Probable G-protein coupled receptor 88, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total) |
Functional Keywords | gpr88, signaling complex, cryo-em, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 157259.50 |
Authors | |
Primary citation | Chen, G.,Xu, J.,Inoue, A.,Schmidt, M.F.,Bai, C.,Lu, Q.,Gmeiner, P.,Liu, Z.,Du, Y. Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex. Nat Commun, 13:2375-2375, 2022 Cited by PubMed: 35501348DOI: 10.1038/s41467-022-30081-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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