7DOC
Crystal structure of Zika NS2B-NS3 protease with compound 5
Summary for 7DOC
Entry DOI | 10.2210/pdb7doc/pdb |
Descriptor | Core protein, Genome polyprotein, Serine protease subunit NS2B, ... (9 entities in total) |
Functional Keywords | viral protease, protease inhibitor complex, viral protein |
Biological source | Zika virus (ZIKV) More |
Total number of polymer chains | 9 |
Total formula weight | 83956.59 |
Authors | Quek, J.P. (deposition date: 2020-12-14, release date: 2021-04-14, Last modification date: 2024-07-10) |
Primary citation | Patil, N.A.,Quek, J.P.,Schroeder, B.,Morewood, R.,Rademann, J.,Luo, D.,Nitsche, C. 2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease. Acs Med.Chem.Lett., 12:732-737, 2021 Cited by PubMed: 34055219DOI: 10.1021/acsmedchemlett.0c00657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.904 Å) |
Structure validation
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