7DMQ
Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex
Summary for 7DMQ
Entry DOI | 10.2210/pdb7dmq/pdb |
EMDB information | 30767 |
Descriptor | CRISPR/Cas system Cas13a, CRISPR RNA, Anti-tag target RNA (3 entities in total) |
Functional Keywords | type vi-a crispr-cas system, cas13a, anti-tag rna, inhibition, immune system, immune system-rna complex, immune system/rna |
Biological source | Leptotrichia shahii More |
Total number of polymer chains | 3 |
Total formula weight | 197146.77 |
Authors | Wang, B.,Zhang, T.,Ding, J.,Patel, D.J.,Yang, H. (deposition date: 2020-12-05, release date: 2021-02-10, Last modification date: 2024-03-27) |
Primary citation | Wang, B.,Zhang, T.,Yin, J.,Yu, Y.,Xu, W.,Ding, J.,Patel, D.J.,Yang, H. Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems. Mol.Cell, 81:1100-, 2021 Cited by PubMed: 33472057DOI: 10.1016/j.molcel.2020.12.033 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.06 Å) |
Structure validation
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