7DFZ
Cryo_EM structure of delta N-NPC1L1-EZE
Summary for 7DFZ
Entry DOI | 10.2210/pdb7dfz/pdb |
EMDB information | 30668 |
Descriptor | NPC1-like intracellular cholesterol transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | ezetimibe, structural protein-inhibitor complex, structural protein/inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 145608.98 |
Authors | |
Primary citation | Hu, M.,Yang, F.,Huang, Y.,You, X.,Liu, D.,Sun, S.,Sui, S.F. Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. Sci Adv, 7:-, 2021 Cited by PubMed: 34272236DOI: 10.1126/sciadv.abg3188 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.58 Å) |
Structure validation
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