7DFZ
Cryo_EM structure of delta N-NPC1L1-EZE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NPC1-like intracellular cholesterol transporter 1 | polymer | 1273 | 139612.1 | 1 | UniProt (A0A0C4DFX6) Pfam (PF16414) Pfam (PF22314) Pfam (PF12349) Pfam (PF02460) UniProt (by SIFTS) (Q9UHC9) | Homo sapiens (Human) | |
| 2 | B, E (E, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 2 | In PDB GlyTouCan (G11411VI) | |||
| 3 | C (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G79924RM) | |||
| 4 | D, F (J, T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 2 | In PDB GlyTouCan (G47362BJ) | |||
| 5 | G, H, I, J, K (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 6 | L (A) | (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one | non-polymer | 409.4 | 1 | Chemie (H56) | |||
| 7 | M, N, O, P (A) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 139612.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2934.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3062.1 | |
| All* | Total formula weight | 145609.0 |
