7DA5
Cryo-EM structure of the human MCT1 D309N mutant in complex with Basigin-2 in the inward-open conformation.
Summary for 7DA5
Entry DOI | 10.2210/pdb7da5/pdb |
Related | 6LYY 6LZ0 7CKO 7CKR |
EMDB information | 30623 |
Descriptor | Monocarboxylate transporter 1, Basigin (2 entities in total) |
Functional Keywords | proton-coupled monocarboxylate transporter, mct1, basigin, azd3965, single particle cryo-em, latate transporter, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 83246.80 |
Authors | |
Primary citation | Wang, N.,Jiang, X.,Zhang, S.,Zhu, A.,Yuan, Y.,Xu, H.,Lei, J.,Yan, C. Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates. Cell, 184:370-, 2021 Cited by PubMed: 33333023DOI: 10.1016/j.cell.2020.11.043 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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