7CY8
Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C
Summary for 7CY8
Entry DOI | 10.2210/pdb7cy8/pdb |
Descriptor | Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), ASCORBIC ACID, ... (7 entities in total) |
Functional Keywords | tet, vitamin c, dioxygenase, 5gmc, dna modification, 2-oxoglutarate, transferase |
Biological source | Escherichia coli More |
Total number of polymer chains | 3 |
Total formula weight | 107953.26 |
Authors | |
Primary citation | Li, W.,Zhang, T.,Sun, M.,Shi, Y.,Zhang, X.J.,Xu, G.L.,Ding, J. Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12:744-744, 2021 Cited by PubMed: 33531488DOI: 10.1038/s41467-021-21061-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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