7CXA

Structure of human Galectin-3 CRD in complex with TD-139 belonging to P31 space group.

Summary for 7CXA

Entry DOI	10.2210/pdb7cxa/pdb
Related	7CXB 7CXC 7CXD
Descriptor	Galectin-3, CHLORIDE ION, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, ... (4 entities in total)
Functional Keywords	beta-galactose binding protein, carbohydrate, sugar binding protein, td-139
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	38498.50
Authors	Kumar, A. (deposition date: 2020-09-01, release date: 2021-09-01, Last modification date: 2023-11-29)
Primary citation	Kumar, A.,Paul, M.,Panda, M.,Jayaram, S.,Kalidindi, N.,Sale, H.,Vetrichelvan, M.,Gupta, A.,Mathur, A.,Beno, B.,Regueiro-Ren, A.,Cheng, D.,Ramarao, M.,Ghosh, K. Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology, 31:1390-1400, 2021 Cited by PubMed: 34228782 DOI: 10.1093/glycob/cwab072 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation