7CJL
Metallo-Beta-Lactamase VIM-2 in complex with (S)-N-(3-(2H-tetrazol-5-yl)phenyl)-3-mercapto-2-methylpropanamide
Summary for 7CJL
Entry DOI | 10.2210/pdb7cjl/pdb |
Descriptor | Beta-lactamase class B VIM-2, ZINC ION, FORMIC ACID, ... (5 entities in total) |
Functional Keywords | metallo-beta-lactamase vim-2, vim-2, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 50193.18 |
Authors | |
Primary citation | Yan, Y.H.,Chen, J.,Zhan, Z.,Yu, Z.J.,Li, G.,Guo, L.,Li, G.B.,Wu, Y.,Zheng, Y. Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-beta-lactamase inhibitors. Rsc Adv, 10:31377-31384, 2020 Cited by PubMed: 35520685DOI: 10.1039/d0ra06405j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.789 Å) |
Structure validation
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