7C2K

COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex

Summary for 7C2K

• Entry DOI: 10.2210/pdb7c2k/pdb
• EMDB information: 30275
• Descriptor: RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (6 entities in total)
• Functional Keywords: covid-19, 2019-ncov, sars-cov-2, virus, rdrp, nsp12, nsp7, nsp8, rtc, cryo-em, viral protein, rna polymerase, drug target, antiviral, pre-translocated catalytic complex, viral protein-rna complex, viral protein/rna
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 177127.99

Authors

Wang, Q.,Gao, Y.,Ji, W.,Mu, A.,Rao, Z. (deposition date: 2020-05-07, release date: 2020-06-03, Last modification date: 2024-03-27)

• Primary citation: Wang, Q.,Wu, J.,Wang, H.,Gao, Y.,Liu, Q.,Mu, A.,Ji, W.,Yan, L.,Zhu, Y.,Zhu, C.,Fang, X.,Yang, X.,Huang, Y.,Gao, H.,Liu, F.,Ge, J.,Sun, Q.,Yang, X.,Xu, W.,Liu, Z.,Yang, H.,Lou, Z.,Jiang, B.,Guddat, L.W.,Gong, P.,Rao, Z.; Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.; Cell, 182:417-428.e13, 2020; PubMed: 32526208; DOI: 10.1016/j.cell.2020.05.034

Experimental method

ELECTRON MICROSCOPY (2.93 Å)