7BJV
Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI09181
Summary for 7BJV
Entry DOI | 10.2210/pdb7bjv/pdb |
Descriptor | Ultraspiracle protein, Ecdysone Receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (7 entities in total) |
Functional Keywords | nuclear receptor, ligand-binding domain, ecdysone receptor, dibenzoylhydrazine, transcription |
Biological source | Heliothis virescens (Tobacco budworm moth) More |
Total number of polymer chains | 6 |
Total formula weight | 184401.38 |
Authors | Browning, C.,McEwen, A.G.,Billas, I.M.L. (deposition date: 2021-01-14, release date: 2021-04-07, Last modification date: 2024-01-31) |
Primary citation | Browning, C.,McEwen, A.G.,Mori, K.,Yokoi, T.,Moras, D.,Nakagawa, Y.,Billas, I.M.L. Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. J Pestic Sci, 46:88-100, 2021 Cited by PubMed: 33746550DOI: 10.1584/jpestics.D20-095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
Download full validation report