7BB0
Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24)
Summary for 7BB0
Entry DOI | 10.2210/pdb7bb0/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (R)-3,3-dimethyl-5-oxo-5-(6-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pentanoic acid, ... (4 entities in total) |
Functional Keywords | phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase |
Biological source | Cricetulus griseus (Chinese hamster) More |
Total number of polymer chains | 2 |
Total formula weight | 43750.60 |
Authors | Oebbeke, M.,Mueller, J.,Glinca, S.,Heine, A.,Klebe, G. (deposition date: 2020-12-16, release date: 2022-01-12, Last modification date: 2024-01-31) |
Primary citation | Oebbeke, M.,Mueller, J.,Heine, A.,Klebe, G. Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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