6ZYH
Crystal structure of GRP78 (70kDa heat shock protein 5 / BiP) ATPase domain in complex with ADP and calcium
Summary for 6ZYH
Entry DOI | 10.2210/pdb6zyh/pdb |
Descriptor | Endoplasmic reticulum chaperone BiP, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | bip, hsp70, grp78, atpase domain, nbd, adp, chaperone |
Biological source | Cricetulus griseus (Chinese hamster) |
Total number of polymer chains | 2 |
Total formula weight | 84751.60 |
Authors | Yan, Y.,Preissler, S.,Ron, D. (deposition date: 2020-08-01, release date: 2020-12-16, Last modification date: 2024-01-31) |
Primary citation | Preissler, S.,Rato, C.,Yan, Y.,Perera, L.A.,Czako, A.,Ron, D. Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife, 9:-, 2020 Cited by PubMed: 33295873DOI: 10.7554/eLife.62601 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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