6ZX9

Crystal structure of SIV Vpr,fused to T4 lysozyme, isolated from moustached monkey, bound to human DDB1 and human DCAF1 (amino acid residues 1046-1396)

6ZX9 の概要

• エントリーDOI: 10.2210/pdb6zx9/pdb
• 分子名称: DNA damage-binding protein 1, DDB1- and CUL4-associated factor 1, Vpr protein fused to T4 lysozyme, ... (6 entities in total)
• 機能のキーワード: viral protein vpr, viral hijacking of human ubiquitin ligase crl4, ddb1, dcaf1, viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 198623.62

構造登録者

Schwefel, D.,Banchenko, S. (登録日: 2020-07-29, 公開日: 2021-07-21, 最終更新日: 2024-01-31)

• 主引用文献: Banchenko, S.,Krupp, F.,Gotthold, C.,Burger, J.,Graziadei, A.,O'Reilly, F.J.,Sinn, L.,Ruda, O.,Rappsilber, J.,Spahn, C.M.T.,Mielke, T.,Taylor, I.A.,Schwefel, D.; Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.; Plos Pathog., 17:e1009775-e1009775, 2021; PubMed: 34339457; DOI: 10.1371/journal.ppat.1009775

実験手法

X-RAY DIFFRACTION (2.5197288426 Å)