6ZT0

Crystal structure of the Eiger TNF domain/Grindelwald extracellular domain complex

This is a non-PDB format compatible entry.

Summary for 6ZT0

• Entry DOI: 10.2210/pdb6zt0/pdb
• Descriptor: Protein eiger, Protein grindelwald, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: tnf receptor, jnk cascade, tnf, signaling, extracellular, tumor necrosis factor, signaling protein
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 2
• Total formula weight: 22652.11

Authors

Palmerini, V.,Cecatiello, V.,Pasqualato, S.,Mapelli, M. (deposition date: 2020-07-17, release date: 2021-03-03, Last modification date: 2024-01-31)

• Primary citation: Palmerini, V.,Monzani, S.,Laurichesse, Q.,Loudhaief, R.,Mari, S.,Cecatiello, V.,Olieric, V.,Pasqualato, S.,Colombani, J.,Andersen, D.S.,Mapelli, M.; Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions.; Nat Commun, 12:2070-2070, 2021; PubMed: 33824334; DOI: 10.1038/s41467-021-22080-9

Experimental method

X-RAY DIFFRACTION (2.02 Å)