6ZT0

Crystal structure of the Eiger TNF domain/Grindelwald extracellular domain complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 501

Chain	Residue
A	SER310
A	TYR311
A	GLN312
A	GLN312

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 502

Chain	Residue
A	HOH646
A	GLY303
A	THR317
A	GLY320
A	PHE410
A	HOH608

---

site_id	AC3
Number of Residues	7
Details	binding site for residue EDO A 503

Chain	Residue
A	HIS290
A	GLY292
A	SER293
A	PHE350
A	ASP353
A	HIS389
A	LYS391

---

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LtVTnTGLYYVyaQIcY

Chain	Residue	Details
A	LEU322-TYR338

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	137
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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