6ZCZ

Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody.

6ZCZ の概要

• エントリーDOI: 10.2210/pdb6zcz/pdb
• 分子名称: Spike protein S1, Nanobody, EY6A heavy chain, ... (7 entities in total)
• 機能のキーワード: ey6a, rbd, spike glycoprotein, sars-cov-2, human neutralizing antibody, viral protein, immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 87950.27

構造登録者

Zhou, D.,Zhao, Y.,Fry, E.E.,Ren, J.,Stuart, D.I. (登録日: 2020-06-12, 公開日: 2020-06-24, 最終更新日: 2024-01-24)

• 主引用文献: Zhou, D.,Duyvesteyn, H.M.E.,Chen, C.P.,Huang, C.G.,Chen, T.H.,Shih, S.R.,Lin, Y.C.,Cheng, C.Y.,Cheng, S.H.,Huang, Y.C.,Lin, T.Y.,Ma, C.,Huo, J.,Carrique, L.,Malinauskas, T.,Ruza, R.R.,Shah, P.N.M.,Tan, T.K.,Rijal, P.,Donat, R.F.,Godwin, K.,Buttigieg, K.R.,Tree, J.A.,Radecke, J.,Paterson, N.G.,Supasa, P.,Mongkolsapaya, J.,Screaton, G.R.,Carroll, M.W.,Gilbert-Jaramillo, J.,Knight, M.L.,James, W.,Owens, R.J.,Naismith, J.H.,Townsend, A.R.,Fry, E.E.,Zhao, Y.,Ren, J.,Stuart, D.I.,Huang, K.A.; Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.; Nat.Struct.Mol.Biol., 27:950-958, 2020; PubMed: 32737466; DOI: 10.1038/s41594-020-0480-y

実験手法

X-RAY DIFFRACTION (2.65 Å)