6ZCP

SYK Kinase domain in complex with azabenzimidazole inhibitor 2b

Summary for 6ZCP

Entry DOI	10.2210/pdb6zcp/pdb
Descriptor	Tyrosine-protein kinase SYK, 7-[[4-[4-[(dimethylamino)methyl]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{N},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide (3 entities in total)
Functional Keywords	syk kinase transferase inhibitor, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	35286.42
Authors	Read, J.A. (deposition date: 2020-06-11, release date: 2021-06-23, Last modification date: 2024-01-24)
Primary citation	Read, J.A. SYK Kinase domain in complex with azabenzimidazole inhibitor 4 To Be Published,
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation