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6ZC0

SYK Kinase domain in complex with azabenzimidazole inhibitor 2b

Summary for 6ZC0
Entry DOI10.2210/pdb6zc0/pdb
DescriptorTyrosine-protein kinase SYK, ~{N},~{N}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{H}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine (3 entities in total)
Functional Keywordssyk kinase transferase inhibitor, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight35252.41
Authors
Read, J.A. (deposition date: 2020-06-09, release date: 2021-06-23, Last modification date: 2024-01-24)
Primary citationRead, J.A.
SYK Kinase domain in complex with azabenzimidazole inhibitor 2b
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

226707

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