6Z90

Crystal structure of MINDY1 mutant-P138A

Summary for 6Z90

Entry DOI	10.2210/pdb6z90/pdb
Descriptor	Ubiquitin carboxyl-terminal hydrolase MINDY-1 (1 entity in total)
Functional Keywords	hydrolase, cysteine protease, isopeptidase and ubiquitin binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	32012.18
Authors	Abdul Rehman, S.A.,Kulathu, Y. (deposition date: 2020-06-03, release date: 2021-06-30, Last modification date: 2024-01-24)
Primary citation	Abdul Rehman, S.A.,Armstrong, L.A.,Lange, S.M.,Kristariyanto, Y.A.,Grawert, T.W.,Knebel, A.,Svergun, D.I.,Kulathu, Y. Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81:4176-4190.e6, 2021 Cited by PubMed: 34529927 DOI: 10.1016/j.molcel.2021.08.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.59 Å)

Structure validation