6Z72

SARS-CoV-2 Macrodomain in complex with ADP-HPM

Summary for 6Z72

Entry DOI	10.2210/pdb6z72/pdb
Descriptor	Replicase polyprotein 1ab, Adenosine Diphosphate (Hydroxymethyl)pyrrolidine monoalcohol, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	viral macrodomain, adp-ribose binding module, adp-ribosylhydrolase, adp-ribosylation, viral protein, adp-hpm
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	4
Total formula weight	78680.38
Authors	Zorzini, V.,Rack, J.,Ahel, I. (deposition date: 2020-05-29, release date: 2020-12-02, Last modification date: 2024-01-24)
Primary citation	Rack, J.G.M.,Zorzini, V.,Zhu, Z.,Schuller, M.,Ahel, D.,Ahel, I. Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential. Open Biology, 10:200237-200237, 2020 Cited by PubMed: 33202171 DOI: 10.1098/rsob.200237 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation