6Z6V

Globular head of C1q in complex with the nanobody C1qNb75

Summary for 6Z6V

• Entry DOI: 10.2210/pdb6z6v/pdb
• Related: 5hzf
• Descriptor: Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... (6 entities in total)
• Functional Keywords: complement, antibody, nanobody, c1q, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 122353.12

Authors

Laursen, N.S.,Andersen, G.R. (deposition date: 2020-05-29, release date: 2020-06-10, Last modification date: 2024-01-24)

• Primary citation: Laursen, N.S.,Pedersen, D.V.,Gytz, H.,Zarantonello, A.,Bernth Jensen, J.M.,Hansen, A.G.,Thiel, S.,Andersen, G.R.; Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.; Front Immunol, 11:1504-1504, 2020; PubMed: 32849513; DOI: 10.3389/fimmu.2020.01504

Experimental method

X-RAY DIFFRACTION (2.19 Å)