6Z58

Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003791

Summary for 6Z58

• Entry DOI: 10.2210/pdb6z58/pdb
• Descriptor: Serine/threonine-protein kinase haspin, 8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one, SODIUM ION, ... (5 entities in total)
• Functional Keywords: kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41174.02

Authors

Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003791; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)