6Z57

Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078

Summary for 6Z57

• Entry DOI: 10.2210/pdb6z57/pdb
• Descriptor: Serine/threonine-protein kinase haspin, 10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene, SODIUM ION, ... (7 entities in total)
• Functional Keywords: kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41573.61

Authors

Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)