6Z57
Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078
Summary for 6Z57
Entry DOI | 10.2210/pdb6z57/pdb |
Descriptor | Serine/threonine-protein kinase haspin, 10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene, SODIUM ION, ... (7 entities in total) |
Functional Keywords | kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41573.61 |
Authors | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24) |
Primary citation | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report