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6Z52

Crystal structure of CLK3 in complex with macrocycle ODS2003136

Summary for 6Z52
Entry DOI10.2210/pdb6z52/pdb
DescriptorDual specificity protein kinase CLK3, 1,2-ETHANEDIOL, CHLORIDE ION, ... (6 entities in total)
Functional Keywordskinase, kinase inhibitor, clk3, macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight88133.16
Authors
Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24)
Primary citationChaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC)
Crystal structure of CLK3 in complex with macrocycle ODS2003136
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.12 Å)
Structure validation

222624

건을2024-07-17부터공개중

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