6Z4A

Structure of the human SAS-6 N-terminal domain, F131E mutant

Summary for 6Z4A

Entry DOI	10.2210/pdb6z4a/pdb
Descriptor	Spindle assembly abnormal protein 6 homolog, GLYCEROL (3 entities in total)
Functional Keywords	centrosome, centriole, cartwheel, alpha/beta protein, structural protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	17837.63
Authors	Busch, J.M.C.,Vakonakis, I. (deposition date: 2020-05-25, release date: 2020-09-09, Last modification date: 2024-02-07)
Primary citation	Busch, J.M.C.,Matsoukas, M.T.,Musgaard, M.,Spyroulias, G.A.,Biggin, P.C.,Vakonakis, I. Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization. J.Biol.Chem., 295:17922-17934, 2020 Cited by PubMed: 32873708 DOI: 10.1074/jbc.RA120.014780 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation