7PEL
CryoEM structure of simian T-cell lymphotropic virus intasome in complex with PP2A regulatory subunit B56 gamma
Replaces: 6Z2YSummary for 7PEL
Entry DOI | 10.2210/pdb7pel/pdb |
Related | 6QBT 6QBV 6QBW 6TJU 6TOQ |
EMDB information | 11052 |
Descriptor | Pol protein, Isoform 3 of PC4 and SFRS1-interacting protein,Isoform Gamma-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), ... (5 entities in total) |
Functional Keywords | integrase, transferase, deltaretrovirus, pp2a, b56, phosphatase, molecular mimicry, host factor, dna-binding, viral protein |
Biological source | Simian T-lymphotropic virus 1 More |
Total number of polymer chains | 10 |
Total formula weight | 332223.95 |
Authors | Barski, M.,Pye, V.E.,Nans, A.,Cherepanov, P.,Maertens, G.N. (deposition date: 2021-08-10, release date: 2021-08-25, Last modification date: 2024-07-10) |
Primary citation | Barski, M.S.,Minnell, J.J.,Hodakova, Z.,Pye, V.E.,Nans, A.,Cherepanov, P.,Maertens, G.N. Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56gamma. Nat Commun, 11:5043-, 2020 Cited by PubMed: 33028863DOI: 10.1038/s41467-020-18874-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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