6Z2P
Crystal structure of catalytic inactive OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (glycodrosocin) substrate
Summary for 6Z2P
Entry DOI | 10.2210/pdb6z2p/pdb |
Related PRD ID | PRD_900084 |
Descriptor | O-glycan protease, Glycodrosocin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, ... (5 entities in total) |
Functional Keywords | o-glycan endopeptidase, mucins, ogpa. metalloprotease, hydrolase |
Biological source | Akkermansia muciniphila ATCC BAA-835 More |
Total number of polymer chains | 2 |
Total formula weight | 44359.04 |
Authors | Trastoy, B.,Naegali, A.,Anso, I.,Sjogren, J.,Guerin, M.E. (deposition date: 2020-05-18, release date: 2020-09-30, Last modification date: 2024-01-24) |
Primary citation | Trastoy, B.,Naegeli, A.,Anso, I.,Sjogren, J.,Guerin, M.E. Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila. Nat Commun, 11:4844-4844, 2020 Cited by PubMed: 32973204DOI: 10.1038/s41467-020-18696-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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