6YS0
Transaldolase variant D211A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Summary for 6YS0
Entry DOI | 10.2210/pdb6ys0/pdb |
Related | 6YR3 6YRE 6YRH 6YRM 6YRT |
Descriptor | Probable transaldolase, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | alpha-beta barrel, conformational selection, domain swapping, transferase, tim barrel, schiff base, large-scale motions, substrate binding, rate-determining product release |
Biological source | Thermoplasma acidophilum DSM 1728 |
Total number of polymer chains | 5 |
Total formula weight | 124526.28 |
Authors | Sautner, V.,Klaus, M.,Tittmann, K. (deposition date: 2020-04-20, release date: 2021-05-12, Last modification date: 2024-01-24) |
Primary citation | Sautner, V.,Lietzow, T.H.,Klaus, M.,Funk, L.M.,Tittmann, K. Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release To Be Published, |
Experimental method |
Structure validation
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