6YRT
Transaldolase variant T30D from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Summary for 6YRT
Entry DOI | 10.2210/pdb6yrt/pdb |
Related | 6YR3 6YRE 6YRH 6YRM |
Descriptor | Transaldolase, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | alpha-beta barrel, conformational selection, domain swapping, transferase, tim barrel, schiff base, large-scale motions, substrate binding, rate-determining product release |
Biological source | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
Total number of polymer chains | 5 |
Total formula weight | 124816.25 |
Authors | Sautner, V.,Klaus, M.,Tittmann, K. (deposition date: 2020-04-20, release date: 2021-05-12, Last modification date: 2024-01-24) |
Primary citation | Sautner, V.,Lietzow, T.H.,Klaus, M.,Funk, L.M.,Tittmann, K. Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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