6YPX

Human histidine triad nucleotide-binding protein 2 (hHINT2) refined to 2.11 A in C2221 space group

これはPDB形式変換不可エントリーです。

「4NJZ」から置き換えられました

6YPX の概要

• エントリーDOI: 10.2210/pdb6ypx/pdb
• 関連するPDBエントリー: 6YI0 6YPR
• 分子名称: Histidine triad nucleotide-binding protein 2, mitochondrial, CACODYLATE ION, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: nucleotide binding protein, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 69239.05

構造登録者

Dolot, R.D.,Wlodarczyk, A.,Bujacz, G.D.,Nawrot, B.C. (登録日: 2020-04-16, 公開日: 2020-04-29, 最終更新日: 2024-01-24)

主引用文献

Dolot, R.,Krakowiak, A.,Kaczmarek, R.,Wlodarczyk, A.,Pichlak, M.,Nawrot, B.
Biochemical, crystallographic and biophysical characterization of histidine triad nucleotide-binding protein 2 with different ligands including a non-hydrolyzable analog of Ap4A.
Biochim Biophys Acta Gen Subj, 1865:129968-129968, 2021

PubMed Abstract: Human HINT2 is an important mitochondrial enzyme involved in many processes such as apoptosis and bioenergetics, but its endogenous substrates and the three-dimensional structure of the full-length protein have not been identified yet.

PubMed: 34329705
DOI: 10.1016/j.bbagen.2021.129968

実験手法

X-RAY DIFFRACTION (2.11 Å)