6YOU

Crystal structure of the cAMP-dependent protein kinase A in complex with Pyrido[3,2-d]pyrimidin-4-amine (soaked)

Summary for 6YOU

• Entry DOI: 10.2210/pdb6you/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, pyrido[3,2-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• Biological source: Cricetulus griseus (Chinese hamster)
• Total number of polymer chains: 1
• Total formula weight: 41339.89

Authors

Oebbeke, M.,Heine, A.,Klebe, G. (deposition date: 2020-04-15, release date: 2021-04-28, Last modification date: 2024-11-13)

• Primary citation: Oebbeke, M.,Wienen-Schmidt, B.,Gerber, H.-D.,Heine, A.,Klebe, G.; Fragment based drug design - Small chemical changes of fragments effecting big changes in binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.73 Å)