Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6YNT

Crystal structure of the cAMP-dependent protein kinase A in complex with aminofasudil and PKI (5-24)

Summary for 6YNT
Entry DOI10.2210/pdb6ynt/pdb
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (7 entities in total)
Functional Keywordsphosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
Biological sourceCricetulus griseus (Chinese hamster)
More
Total number of polymer chains2
Total formula weight44157.35
Authors
Oebbeke, M.,Gerber, H.-D.,Heine, A.,Klebe, G. (deposition date: 2020-04-14, release date: 2020-10-14, Last modification date: 2024-01-24)
Primary citationWienen-Schmidt, B.,Oebbeke, M.,Ngo, K.,Heine, A.,Klebe, G.
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding Poses.
Chemmedchem, 16:292-300, 2021
Cited by
PubMed: 33029876
DOI: 10.1002/cmdc.202000565
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.52 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon