6YMD

Crystal structure of serine hydroxymethyltransferase from Aphanothece halophytica in the covalent complex with malonate

Summary for 6YMD

Entry DOI	10.2210/pdb6ymd/pdb
Descriptor	Serine hydroxymethyltransferase, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	serine biosynthesis, glycine, plp, one-carbon metabolism, tetrahydrofolate, transferase
Biological source	Aphanothece halophytica
Total number of polymer chains	2
Total formula weight	98368.83
Authors	Ruszkowski, M.,Sekula, B.,Nogues, I.,Tramonti, A.,Angelaccio, S.,Contestabile, R. (deposition date: 2020-04-08, release date: 2020-06-03, Last modification date: 2024-01-24)
Primary citation	Nogues, I.,Tramonti, A.,Angelaccio, S.,Ruszkowski, M.,Sekula, B.,Contestabile, R. Structural and kinetic properties of serine hydroxymethyltransferase from the halophytic cyanobacterium Aphanothece halophytica provide a rationale for salt tolerance. Int.J.Biol.Macromol., 159:517-529, 2020 Cited by PubMed: 32417544 DOI: 10.1016/j.ijbiomac.2020.05.081 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation