6YMD

Crystal structure of serine hydroxymethyltransferase from Aphanothece halophytica in the covalent complex with malonate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine hydroxymethyltransferase	polymer	447	48656.0	2	UniProt (I7H6W6) Pfam (PF00464)	Aphanothece halophytica	Serine methylase
2	C, I (A, B)	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE	non-polymer		248.2	2	Chemie (PMP)
3	D, E, J, K, L (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
4	F, H (A, B)	MALONATE ION	non-polymer		102.0	2	Chemie (MLI)
5	G, M (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
6	N, O (A, B)	water	water		18.0	901	Chemie (HOH)

Sequence modifications

A, B: 1 - 427 (UniProt: I7H6W6)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97312.1
Non-Polymers*	Number of molecules	11
	Total formula weight	1056.8
All*	Total formula weight	98368.8

*Water molecules are not included.