6YH1

tRNA-guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized complex with 6-amino-2-(methylamino)-4-(4-(trifluoromethyl)phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

6YH1 の概要

• エントリーDOI: 10.2210/pdb6yh1/pdb
• 関連するPDBエントリー: 6YGS
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-(methylamino)-4-(4-(trifluoromethyl)phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• 機能のキーワード: transferase, tgt, trna-guanine transglycosylase, guanine insertion enzyme, homodimer, 19f nmr
• 由来する生物種: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43609.57

構造登録者

Nguyen, A.,Heine, A.,Klebe, G. (登録日: 2020-03-28, 公開日: 2020-04-08, 最終更新日: 2024-01-24)

• 主引用文献: Nguyen, A.,Heine, A.,Klebe, G.; Co-crystallization, nanoESI-MS and 19F NMR reveal dimer disturbing inhibitors and conformational changes at dimer contacts; To Be Published,

実験手法

X-RAY DIFFRACTION (1.55 Å)