6YGS

tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-(methylamino)-4-(4-(trifluoromethyl)phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Summary for 6YGS

• Entry DOI: 10.2210/pdb6ygs/pdb
• Related: 6YGR
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-(methylamino)-4-(4-(trifluoromethyl)phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total)
• Functional Keywords: transferase, tgt, trna-guanine transglycosylase, guanine insertion enzyme, homodimer
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 1
• Total formula weight: 43629.70

Authors

Nguyen, A.,Heine, A.,Klebe, G. (deposition date: 2020-03-27, release date: 2020-04-08, Last modification date: 2024-01-24)

• Primary citation: Nguyen, A.,Heine, A.,Klebe, G.; Co-crystallization and 19F NMR reveal dimer disturbing inhibitors and conformational changes at dimer contacts; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)