6YGY

tRNA-Guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized complex with 6-Amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Summary for 6YGY

• Entry DOI: 10.2210/pdb6ygy/pdb
• Related: 6YGZ
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-[2-(4-METHYLPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (4 entities in total)
• Functional Keywords: transferase, tgt, trna-guanine transglycosylase, guanine insertion enzyme, homodimer, 19f nmr
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 1
• Total formula weight: 43526.56

Authors

Nguyen, A.,Heine, A.,Klebe, G. (deposition date: 2020-03-28, release date: 2020-04-08, Last modification date: 2024-01-24)

• Primary citation: Nguyen, A.,Heine, A.,Klebe, G.; Co-crystallization, nanoESI-MS and 19F NMR reveal dimer disturbing inhibitors and conformational changes at dimer contacts; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.52 Å)