6YFZ
Crystal structure of MKK7 (MAP2K7), apo form
Summary for 6YFZ
| Entry DOI | 10.2210/pdb6yfz/pdb |
| Descriptor | Dual specificity mitogen-activated protein kinase kinase 7 (2 entities in total) |
| Functional Keywords | kinase, kinase inhibitor, mkk7, mek7, map2k7, map2k, mek, jnk signaling, structural genomics, structural genomics consortium, sgc, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34944.62 |
| Authors | Chaikuad, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-03-27, release date: 2020-08-12, Last modification date: 2024-01-24) |
| Primary citation | Schroder, M.,Tan, L.,Wang, J.,Liang, Y.,Gray, N.S.,Knapp, S.,Chaikuad, A. Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Cell Chem Biol, 27:1285-1295.e4, 2020 Cited by PubMed: 32783966DOI: 10.1016/j.chembiol.2020.07.014 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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