6Y9B
Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments
Summary for 6Y9B
Entry DOI | 10.2210/pdb6y9b/pdb |
EMDB information | 10735 |
Descriptor | Metalloreductase STEAP1, Fab120.545 light chain, Fab120.545 heavy chain, ... (5 entities in total) |
Functional Keywords | integral membrane protein heme-binding protein oxidoreductase antibody-antigen complex, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 287657.92 |
Authors | Oosterheert, W.,Gros, P. (deposition date: 2020-03-06, release date: 2020-05-20, Last modification date: 2020-07-22) |
Primary citation | Oosterheert, W.,Gros, P. Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1). J.Biol.Chem., 295:9502-9512, 2020 Cited by PubMed: 32409586DOI: 10.1074/jbc.RA120.013690 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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