Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005768 | cellular_component | endosome |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005911 | cellular_component | cell-cell junction |
| A | 0010008 | cellular_component | endosome membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005768 | cellular_component | endosome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005911 | cellular_component | cell-cell junction |
| B | 0010008 | cellular_component | endosome membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005768 | cellular_component | endosome |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0005911 | cellular_component | cell-cell junction |
| C | 0010008 | cellular_component | endosome membrane |
| C | 0016020 | cellular_component | membrane |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue HEM C 401 |
| Chain | Residue |
| C | LYS116 |
| C | PHE272 |
| C | THR290 |
| C | PHE291 |
| C | PRO119 |
| C | SER122 |
| C | HIS175 |
| C | ALA176 |
| C | SER179 |
| C | GLY223 |
| C | LEU227 |
| C | HIS268 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue XP4 C 402 |
| Chain | Residue |
| A | LEU232 |
| A | VAL235 |
| C | PHE68 |
| C | GLN70 |
| C | TRP71 |
| C | PHE170 |
| C | VAL173 |
| C | ALA234 |
| C | SER237 |
| C | PRO239 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue HEM A 401 |
| Chain | Residue |
| A | LYS116 |
| A | PRO119 |
| A | SER122 |
| A | HIS175 |
| A | ALA176 |
| A | SER179 |
| A | GLY223 |
| A | LEU227 |
| A | HIS268 |
| A | PHE272 |
| A | THR290 |
| A | PHE291 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue XP4 A 402 |
| Chain | Residue |
| A | PHE68 |
| A | GLN70 |
| A | TRP71 |
| A | PHE170 |
| A | VAL173 |
| A | ALA234 |
| A | SER237 |
| A | PRO239 |
| B | LEU232 |
| B | VAL235 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue HEM B 401 |
| Chain | Residue |
| B | LYS116 |
| B | PRO119 |
| B | SER122 |
| B | HIS175 |
| B | ALA176 |
| B | SER179 |
| B | GLY223 |
| B | LEU227 |
| B | HIS268 |
| B | PHE272 |
| B | THR290 |
| B | PHE291 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue XP4 B 402 |
| Chain | Residue |
| B | PHE68 |
| B | GLN70 |
| B | TRP71 |
| B | PHE170 |
| B | VAL173 |
| B | ALA234 |
| B | SER237 |
| B | PRO239 |
| C | ALA231 |
| C | VAL235 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR198-HIS204 | |
| H | TYR205-HIS211 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 360 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| C | TRP71-LEU91 | |
| A | ILE218-ILE238 | |
| A | GLY258-ILE278 | |
| A | PHE291-PRO311 | |
| B | TRP71-LEU91 | |
| B | PRO119-VAL139 | |
| B | PHE164-MET184 | |
| B | ILE218-ILE238 | |
| B | GLY258-ILE278 | |
| B | PHE291-PRO311 | |
| C | PRO119-VAL139 | |
| C | PHE164-MET184 | |
| C | ILE218-ILE238 | |
| C | GLY258-ILE278 | |
| C | PHE291-PRO311 | |
| A | TRP71-LEU91 | |
| A | PRO119-VAL139 | |
| A | PHE164-MET184 | |
| Chain | Residue | Details |
| C | GLN140 | |
| B | ARG161 | |
| B | SER237 | |
| B | GLN254 | |
| C | ARG161 | |
| C | SER237 | |
| C | GLN254 | |
| A | GLN140 | |
| A | ARG161 | |
| A | SER237 | |
| A | GLN254 | |
| B | GLN140 | |
| Chain | Residue | Details |
| C | HIS175 | |
| C | HIS268 | |
| A | HIS175 | |
| A | HIS268 | |
| B | HIS175 | |
| B | HIS268 | |
