Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005768 | cellular_component | endosome |
A | 0005886 | cellular_component | plasma membrane |
A | 0005911 | cellular_component | cell-cell junction |
A | 0010008 | cellular_component | endosome membrane |
A | 0016020 | cellular_component | membrane |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
A | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
B | 0005515 | molecular_function | protein binding |
B | 0005768 | cellular_component | endosome |
B | 0005886 | cellular_component | plasma membrane |
B | 0005911 | cellular_component | cell-cell junction |
B | 0010008 | cellular_component | endosome membrane |
B | 0016020 | cellular_component | membrane |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
B | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
C | 0005515 | molecular_function | protein binding |
C | 0005768 | cellular_component | endosome |
C | 0005886 | cellular_component | plasma membrane |
C | 0005911 | cellular_component | cell-cell junction |
C | 0010008 | cellular_component | endosome membrane |
C | 0016020 | cellular_component | membrane |
C | 0020037 | molecular_function | heme binding |
C | 0046872 | molecular_function | metal ion binding |
C | 0052851 | molecular_function | ferric-chelate reductase (NADPH) activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | binding site for residue HEM C 401 |
Chain | Residue |
C | LYS116 |
C | PHE272 |
C | THR290 |
C | PHE291 |
C | PRO119 |
C | SER122 |
C | HIS175 |
C | ALA176 |
C | SER179 |
C | GLY223 |
C | LEU227 |
C | HIS268 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for residue XP4 C 402 |
Chain | Residue |
A | LEU232 |
A | VAL235 |
C | PHE68 |
C | GLN70 |
C | TRP71 |
C | PHE170 |
C | VAL173 |
C | ALA234 |
C | SER237 |
C | PRO239 |
site_id | AC3 |
Number of Residues | 12 |
Details | binding site for residue HEM A 401 |
Chain | Residue |
A | LYS116 |
A | PRO119 |
A | SER122 |
A | HIS175 |
A | ALA176 |
A | SER179 |
A | GLY223 |
A | LEU227 |
A | HIS268 |
A | PHE272 |
A | THR290 |
A | PHE291 |
site_id | AC4 |
Number of Residues | 10 |
Details | binding site for residue XP4 A 402 |
Chain | Residue |
A | PHE68 |
A | GLN70 |
A | TRP71 |
A | PHE170 |
A | VAL173 |
A | ALA234 |
A | SER237 |
A | PRO239 |
B | LEU232 |
B | VAL235 |
site_id | AC5 |
Number of Residues | 12 |
Details | binding site for residue HEM B 401 |
Chain | Residue |
B | LYS116 |
B | PRO119 |
B | SER122 |
B | HIS175 |
B | ALA176 |
B | SER179 |
B | GLY223 |
B | LEU227 |
B | HIS268 |
B | PHE272 |
B | THR290 |
B | PHE291 |
site_id | AC6 |
Number of Residues | 10 |
Details | binding site for residue XP4 B 402 |
Chain | Residue |
B | PHE68 |
B | GLN70 |
B | TRP71 |
B | PHE170 |
B | VAL173 |
B | ALA234 |
B | SER237 |
B | PRO239 |
C | ALA231 |
C | VAL235 |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
Chain | Residue | Details |
L | TYR198-HIS204 | |
H | TYR205-HIS211 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 360 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
C | TRP71-LEU91 | |
A | ILE218-ILE238 | |
A | GLY258-ILE278 | |
A | PHE291-PRO311 | |
B | TRP71-LEU91 | |
B | PRO119-VAL139 | |
B | PHE164-MET184 | |
B | ILE218-ILE238 | |
B | GLY258-ILE278 | |
B | PHE291-PRO311 | |
C | PRO119-VAL139 | |
C | PHE164-MET184 | |
C | ILE218-ILE238 | |
C | GLY258-ILE278 | |
C | PHE291-PRO311 | |
A | TRP71-LEU91 | |
A | PRO119-VAL139 | |
A | PHE164-MET184 | |
Chain | Residue | Details |
C | GLN140 | |
B | ARG161 | |
B | SER237 | |
B | GLN254 | |
C | ARG161 | |
C | SER237 | |
C | GLN254 | |
A | GLN140 | |
A | ARG161 | |
A | SER237 | |
A | GLN254 | |
B | GLN140 | |
Chain | Residue | Details |
C | HIS175 | |
C | HIS268 | |
A | HIS175 | |
A | HIS268 | |
B | HIS175 | |
B | HIS268 | |