6Y30
NG domain of human SRP54 T115A mutant
Summary for 6Y30
Entry DOI | 10.2210/pdb6y30/pdb |
Descriptor | Signal recognition particle 54 kDa protein (2 entities in total) |
Functional Keywords | srp54 ng domain, protein translocation, severe congenital neutropenia, disease mutant, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 66687.08 |
Authors | Juaire, K.D.,Wild, K.,Sinning, I. (deposition date: 2020-02-17, release date: 2020-09-23, Last modification date: 2024-01-24) |
Primary citation | Juaire, K.D.,Lapouge, K.,Becker, M.M.M.,Kotova, I.,Michelhans, M.,Carapito, R.,Wild, K.,Bahram, S.,Sinning, I. Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia. Structure, 29:15-, 2021 Cited by PubMed: 33053321DOI: 10.1016/j.str.2020.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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