6XY7
Human SHIP1 with magnesium and phosphate bound to the active site
This is a non-PDB format compatible entry.
Summary for 6XY7
Entry DOI | 10.2210/pdb6xy7/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | phosphatidylinositol, phosphate, phosphatase, alzheimer's disease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 53381.42 |
Authors | Bradshaw, W.J.,Scacioc, A.,Fernandez-Cid, A.,Mckinley, G.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O. (deposition date: 2020-01-29, release date: 2020-02-26, Last modification date: 2024-02-14) |
Primary citation | Bradshaw, W.J.,Kennedy, E.C.,Moreira, T.,Smith, L.A.,Chalk, R.,Katis, V.L.,Benesch, J.L.P.,Brennan, P.E.,Murphy, E.J.,Gileadi, O. Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024 Cited by PubMed: 38309262DOI: 10.1016/j.str.2024.01.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.086 Å) |
Structure validation
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